TABLE 3.
Piglet infectious model
| Site | Control | Mean CFU/g of tissue (SD) for C. jejuni straina: |
||
|---|---|---|---|---|
| NCTC 11168 | ATCC 43431 | 81-176 | ||
| Duodenum | NDb | 3.2 × 105 (2.5 × 105) | 1.1 × 103 (1.2 × 102) | 1.8 × 104 (1.0 × 104) |
| Jejunum | ND | 6.2 × 104 (4.5 × 104) | 1.2 × 105 (1.0 × 105) | 2.8 × 104 (1.0 × 104) |
| Ileum | ND | 9.3 × 104 (4.6 × 104) | 4.2 × 105 (3.9 × 104) | 2.0 × 104 (8.4 × 103) |
| Cecum | ND | 1.5 × 107 (9.1 × 106) | 2.1 × 104 (1.7 × 104) | 7.1 × 103 (2.8 × 103) |
| Colon | ND | 2.8 × 106 (1.3 × 106) | 1.7 × 103 (7.7 × 102) | 1.2 × 105 (6.3 × 104) |
| Diarrhea | Absent | Present | Present | Present |
| Blood in fecesc | Absent | Absent | Present | Present |
a
Three colostrum-deprived piglets were infected orally with approximately 5 × 1010 viable bacteria of each C. jejuni strain. At 3 days postinfection, the piglets were euthanized, and the level of bacterial colonization was determined for each intestinal segment (duodenum, jejunum, ileum, cecum, and colon). The data represent the mean CFU for each strain per gram of tissue.
b
ND, C. jejuni was not detected in the control piglets.
c
The presence of blood in the feces was tested using the EZ detection kit.