Figure 1.

A diagram of the target plasmids. Downward arrows mark the positions of 5′HS2, -3, and -4 of the β-globin LCR (mini-LAR), which is linked upstream of the β- globin (5′HS234-β) and γ-globin (5′HS234-γ) promoters. Horizontal arrows mark the positions of primers used for primer extension in this report, and vertical lines mark the positions of identified transcription factor binding sites in the β- and the γ-globin promoters. Transcription initiation sites of both promoters are indicated with bent arrows.