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. 2006 Oct 11;103(43):15927–15932. doi: 10.1073/pnas.0607661103

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© 2006 by The National Academy of Sciences of the USA

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Fig. 7. — KGDH and PDH complex assays. The KGDH (A and B) and PDH (C and D) complex activities were assayed by measuring NADH formed in the presence or absence of ThPP. (A and C) Wild-type (white bar) and knockout (gray bar) MEFs. (B and D) Human lymphoblasts from a normal individual (white bar) and a MCPHA patient (cross-hatched bar). The data represent the mean ± SEM of three independent experiments in duplicate. ANOVA analysis (two-way) was applied to compare the two groups, with and without ThPP, and ∗∗ denotes significance compared with control (P < 0.05).