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Regulation of the uptake hydrogenase in R. palustris. The HupUV-HoxJA system activates expression of the uptake hydrogenase and other genes indicated in response to hydrogen. RegSR and, to a lesser extent, RPA0981 negatively modulate expression of the uptake hydrogenase, possibly in response to reducing conditions. The hydrogen-dependent regulatory system is similar to that of R. eutropha (27). CM, cytoplasmic membrane.
