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Phenotypic consequences of mutagenizing conserved residues in WhmD. (A) Complementation phenotypes of the four cysteine-to-alanine mutants of WhmD. (B) The inactivation of a conserved aspartate (left) and a glycine (middle) inactivate WhmD. The L116P mutation mimics the inactive S. coelicolor whiB70 allele (right).
