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Effects of substitutions and indels in OSU18 and LVS ORFs
| Category | No. |
|---|---|
| Substitutions | |
| Affected genes | 338 |
| Single substitution | 274 |
| Double substitution | 56 |
| Triple substitution | 7 |
| Quadruple substitution | 1 |
| ORFs with only conservative (silent) substitutions | 158 (97) |
| ORFs with only nonconservative substitutionsa | 180 |
| Indels | |
| Affected genes | 36 |
| Three-amino-acid or less, in frame deletiona | 10 |
| Pseudogene in LVSa | 19 |
Category of polymorphisms that most likely contains LVS attenuating mutations.
