TABLE 2.
S. aureus cold shock-induced transcripts
| Category and qualifiera | Fold inductionb | Common name | Locusc | Description |
|---|---|---|---|---|
| Amino acid metabolism | ||||
| sa_c4601s3932_a_at | 2.4* | rocF | SA2154 | Arginase |
| Carbohydrates | ||||
| sa_c8477s7437_at | 2.8 | SA0869 | Phosphoglycerate mutase | |
| Cell division and cell cycle | ||||
| sa_c1078s861_at | 3.3 | SA1191 | Conserved hypothetical protein | |
| Fatty acids and lipids | ||||
| sa_c6688s5833_a_at | 2.3* | lip | N315-SA2463 | Triacylglycerol lipase precursor |
| sa_c7744s6747_at | 2.5 | SA0621 | Substrate-CoA ligase, putative | |
| Hypothetical | ||||
| sa_c4550s9974_x_at | 2.2 | MSSA476-SAS070 | Conserved hypothetical protein | |
| sa_c7348s6387_a_at | 2.2* | N315-SA0413 | Conserved hypothetical protein | |
| sa_c8469s7429_a_at | 4.1 | N315-SA0751 | Conserved hypothetical protein | |
| sa_c9785s10434_at | 3.3* | N315-SA1186 | Conserved hypothetical protein | |
| sa_c6821s5955_a_at | 15.9* | N315-SA2496 | Conserved hypothetical protein | |
| sa_c3224s2774_a_at | 2.9 | SA0161 | Conserved hypothetical protein | |
| sa_c6917s6037_a_at | 3.4* | SA0299 | Hypothetical protein | |
| sa_c7132s6241_a_at | 2.9* | SA0436 | Conserved hypothetical protein | |
| sa_c7215s6283_a_at | 2.4* | SA0448 | Conserved hypothetical protein | |
| sa_c7352s6391_a_at | 2.8* | SA0497 | Conserved hypothetical protein | |
| sa_c7491s6511_at | 2.2 | SA0537 | Conserved hypothetical protein | |
| sa_c8897s7814_a_at | 2.1* | SA0692 | Conserved hypothetical protein | |
| sa_c485s314_at | 28.0* | SA1033 | Hypothetical protein | |
| sa_c10045s10498_at | 2.8* | SA1372 | Hypothetical protein | |
| sa_c1705s1441_a_at | 3.6 | SA1375 | Conserved hypothetical protein | |
| sa_c1960s1685_a_at | 2.4 | SA1438 | Conserved hypothetical protein | |
| sa_c2254s1952_a_at | 2.2 | SA1524 | Conserved hypothetical protein | |
| sa_c2266s1966_a_at | 2.1 | SA1526 | Conserved hypothetical protein | |
| sa_c2807s2375_a_at | 2.4* | SA1664 | Conserved hypothetical protein | |
| sa_c10133s10545_a_at | 2.3* | SA1777 | Conserved hypothetical | |
| sa_c4628s3951_a_at | 9.2 | SA2162 | Conserved hypothetical protein | |
| sa_c10213s10636_at | 2.1* | SA2218 | Conserved hypothetical protein | |
| sa_c6732s5872_a_at | 3.5 | SA2705 | Hypothetical protein | |
| Miscellaneous | ||||
| sa_c10345s9018_a_at | 3.0* | SA0162 | NAD-dependent formate dehydrogenase | |
| sa_c6230s5410_at | 10.4* | lrgA | SA0247 | Holin-like protein |
| sa_c6266s5446_a_at | 4.7* | lrgB | SA0248 | Holin-like protein |
| Regulation | ||||
| sa_c7020s6143_a_at | 4.4 | SA0404 | Transcriptional regulator, MarR family | |
| sa_c9575s8335_a_at | 5.0 | lexA | SA1374 | LexA repressor |
| Resistance | ||||
| sa_c9464s8272_a_at | 2.2 | yycJ | SA0023 | Metallo-beta-lactamase family |
| sa_c7024s6147_a_at | 2.7 | mepA | SA0405 | MATE efflux family protein |
| Stress response | ||||
| sa_c1956s1681_a_at | 9.3 | cspB | SA2731 | Cold shock protein |
| Transport | ||||
| sa_c5431s4700_a_at | 2.8 | SA0882 | ABC transporter | |
| sa_c8327s7303_a_at | 2.8* | SA0813 | Putative ComF protein 1 | |
| sa_c8331s7308_a_at | 3.9* | SA0814 | Competence protein F | |
| sa_c9678s8436_a_at | 3.5* | SA1601 | Putative competence protein ComGA | |
| sa_c2731s2305_a_at | 2.1* | SA1644 | Putative competence protein | |
| Virulence | ||||
| sa_c10522s10973_s_at | 2.6 | srtA | N315-SA2539 | Sortase |
| sa_c7169s10140_a_at | 7.6 | SA0901 | Pathogenicity island protein | |
| sa_c10151s10571_a_at | 2.4 | SA0902 | Pathogenicity island protein | |
| sa_c3571s9834_a_at | 2.2* | seo | SA1648 | Enterotoxin SeO |
a
Affymetrix S. aureus GeneChip descriptive representing indicated predicted open reading frame (ORF).
b
*, transcript was below the lower limits of sensitivity in unstressed cells and thus the amount of change represents an estimate.
c
S. aureus strain COL locus, unless otherwise indicated (strain preceeds locus identifier).