Table 1.
Clone | Apparent affinity, M | Vκ gene | GenBank accession no. | Jκ gene |
---|---|---|---|---|
R4A* | 9.1 × 10−8 | Vκ1-A | M28131 | Jκ2 |
11-K2C | 4.5 × 10−9 | Vκ1-A | M28131 | Jκ4 |
9-11B9 | 3.6 × 10−9 | Vκ1-A | M28131 | Jκ4 |
E3-B10 | 8.4 × 10−9 | Vκ1-A | M28131 | Jκ4 |
E6-3D9 | 3.7 × 10−7 | Vκ1-A | M28131 | Jκ5 |
11-G5D4 | 7.4 × 10−6 | Vκ-RF | AJ235936 | Jκ1 |
A10-1E4 | 5.4 × 10−6 | Vκ-RF | AJ235936 | Jκ1 |
B15-3C6 | 6.6 × 10−9 | Vκ-RF | AJ235936 | Jκ1 |
C11-1A4 | 2.2 × 10−6 | Vκ-21 | ND | Jκ1 |
E5-3B2 | 1.0 × 10−6 | Vκ-Ser | X02816 | Jκ2 |
A7-1D9 | 2.3 × 10−8 | Vκ-Gx1 | AF021868 | Jκ5 |
B11-1B7 | 4.3 × 10−8 | Vκ-8 | L17135 | Jκ1 |
A7-4(39) | 9.0 × 10−6 | Vκ-21 | ND | Jκ2 |
11-A3C6 | 1.7 × 10−7 | ND | ND | ND |
A7-2G1 | 5.7 × 10−7 | ND | ND | ND |
B1-1(28) | 6.2 × 10−6 | ND | ND | ND |
Clones were obtained from six individual fusions. ND, not determined.
*Original R4A mAb.