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. 2000 Feb 29;97(6):2709–2714. doi: 10.1073/pnas.050567397

Figure 2.

Figure 2

The percent of CD3+CD8+ cells that are CD69+IFN-γ+ in response to autologous B cells pulsed with overlapping peptides spanning the gag protein are shown for three HLA B*57-positive LTNPs (patients 5, 7, and 8) and three HLA B*57-positive progressors (patients 101, 102, and 105). Peptides 15, 17, 23, and 30 contain previously described highly conserved HLA B*57-restricted epitopes shown here in bold (15-QMVHQAISPRTLNAWVKVVE, 17-EKAFSPEVIPMFSALSEGAT, 23-PRGSDIAGTTSTLQEQIGWM and 30-YKTRAEQASQEVKNWMTET). Peptides 1–13 include p17 sequences. The N-terminal sequences of gag beyond peptide 30 (amino acid 320) elicited weak responses and are not shown.