Figure 1.

Virus-specific CD8⁺ T cells in spleen populations from γHV-68-infected I-A^b+/+ mice challenged with recombinant vaccinia viruses. The B6 mice were challenged i.p. with 3 × 10⁷ pfu of the vacc-p56, vacc-p79, or vacc-LCMV^b recombinants 1 mo after i.n. infection with 600 pfu of γHV-68. Spleen populations were enriched for the CD8⁺ set and stained with the p56D^b (A–C) and p79K^b (D and E) tetramers. The results are for a representative animal from each group, with the percent values in the quadrants being for the total lymphocyte population. Cumulated data from three comparable experiments are presented in Table 1.