Figure 3. A ClpA Pseudogene in wOvo Has Many Inactivating Mutations.

An alignment of the nucleotide sequences of ClpA from wMel (a functional gene) and wBm (a pseudogene, inactivated by mutations that generate two in-frame stop codons; otherwise intact), and the partial gene identified from wOvo from fragment OW5. The wOvo gene has multiple, independent, inactivating mutations in the 5′ region available for comparison. Yellow shading indicates in-frame indel events, red shading indicates frame-shifting indel events (observed only in wOvo OW5-K), and violet shading indicates the two in-frame stop codons in wBm ClpA.