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. 2006 Oct 13;2(10):e135. doi: 10.1371/journal.pcbi.0020135

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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The initial conditions and parameters used in the simulation are given in Materials and Methods. The results are shown for three different drug efficacies (ɛ = 0.3, 0.5, and 0.7).

(A) Viral decay profile.

(B) Contribution of long-lived infected cells to plasma virus (φ₁(t) = p_MM*(t) / (NδT*(t) + p_MM*(t))).