Table 1.
LPS, μg
|
Anti-NK1.1-treated WT† | WT (dead/tested) | Tg |
---|---|---|---|
Challenging* | |||
100 | 1 /9 | 0 /5 | |
200 | 1 /6 | 3 /6 | 4 /6 |
300 | 2 /6 | 15 /16 | 14 /17 |
Mice were first primed with the footpad injection of 5 μg of S. marcescens-derived LPS 24 hr before i.v. injection of indicated challenging doses of LPS.
† Mice were treated twice with 100 μl of anti-NK1.1 ascites fluid 4 and 1 days before the priming injection.