Table 3.
Cases | Controls | P value | OR (95% CI) | |
---|---|---|---|---|
A allele at rs1447295 | 989 | 804 | 0.15 | 1.05 (0.95–1.16) |
−8 allele at DG8S737 | 966 | 797 | 0.22 | 1.05 (0.93–1.17) |
Haplotype of A and −8* | 902 | 776 | 0.31 | 1.03 (0.90–1.18) |
Cases diagnosed at <72 years of age and all controls. P values are one-tailed, testing for the previously associated allele (14) being more common (Supplemental Note 3). CI, confidence interval.
*For the haplotype test, we phased the cases and controls together, before carrying out the association analysis.