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E2 induced pituitary growth and hyperprolactinemia similarly in ACI and COP rats. (A) Each data bar represents the mean ± SEM (n = 7–8) pituitary wet weight, which corresponds to pituitary cell number (20). Differing lower case letters above data bars indicate statistical significance (p ≤ 0.05) between group means as assessed by ANOVA. (B) Each data bar represents the mean ± SEM (n = 7–8) level of circulating PRL.
