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The CD38 expression is reduced by surface modulation of MHC Class II molecules. The expression of CD38 and MHC Class II molecules was analyzed on purified monocytes incubated for 18 h in medium alone (1), with an excess of BB51 mAb (2) or with an excess of D1.12 mAb (3). The fluorescence was analyzed on a FACScan flow cytometer with logarithmic amplification. x-axis, fluorescence intensity/cells; y-axis, number of cells/channel. Number of cells analyzed, 10.000.
