Skip to main content
PMC home page
British Medical Journal logoLink to British Medical Journal
. 1980 Jun 28;280(6231):1558–1562. doi: 10.1136/bmj.280.6231.1558

Interferon: therapeutic fact or fiction for the '80s?

G M Scott, D A Tyrrell
PMCID: PMC1601917  PMID: 6159043

Full text

PDF
1562

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aoki F. Y., Crowley J. C. Distribution and removal of human serum albumin-technetium 99m instilled intranasally. Br J Clin Pharmacol. 1976 Oct;3(5):869–878. doi: 10.1111/j.1365-2125.1976.tb00640.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Arvin A. M., Feldman S., Merigan T. C. Human leukocyte interferon in the treatment of varicella in children with cancer: a preliminary controlled trial. Antimicrob Agents Chemother. 1978 Apr;13(4):605–607. doi: 10.1128/aac.13.4.605. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Arvin A. M., Yeager A. S., Merigan T. C. Effect of leukocyte interferon on urinary excretion of cytomegalovirus by infants. J Infect Dis. 1976 Jun;133 (Suppl):A205–A210. doi: 10.1093/infdis/133.supplement_2.a205. [DOI] [PubMed] [Google Scholar]
  4. Best J. M., Banatvala J. E. The effect of a human interferon preparation on vaccine-induced rubella infection. J Biol Stand. 1975;3(1):107–112. doi: 10.1016/0092-1157(75)90013-x. [DOI] [PubMed] [Google Scholar]
  5. Billiau A., De Somers P., Edy V. G., De Clercq E., Heremans H. Human fibroblast interferon for clinical trials: pharmacokinetics and tolerability in experimental animals and humans. Antimicrob Agents Chemother. 1979 Jul;16(1):56–63. doi: 10.1128/aac.16.1.56. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Bridgen P. J., Anfinsen C. B., Corley L., Bose S., Zoon K. C., Rüegg U. T., Buckler C. E. Human lymphoblastoid interferon. Large scale production and partial purification. J Biol Chem. 1977 Oct 10;252(19):6585–6587. [PubMed] [Google Scholar]
  7. Brodeur B. R., Merigan T. C. Mechanism of the suppressive effect of interferon on antibody synthesis in vivo. J Immunol. 1975 Apr;114(4):1323–1328. [PubMed] [Google Scholar]
  8. Cheeseman S. H., Rubin R. H., Stewart J. A., Tolkoff-Rubin N. E., Cosimi A. B., Cantell K., Gilbert J., Winkle S., Herrin J. T., Black P. H. Controlled clinical trial of prophylactic human-leukocyte interferon in renal transplantation. Effects on cytomegalovirus and herpes simplex virus infections. N Engl J Med. 1979 Jun 14;300(24):1345–1349. doi: 10.1056/NEJM197906143002401. [DOI] [PubMed] [Google Scholar]
  9. Desmyter J., De Groote J., Desmet V. J., Billiau A., Ray M. B., Bradburne A. F., Edy V. G., De Somer P. Administration of human fibroblast interferon in chronic hepatitis-B infection. Lancet. 1976 Sep 25;2(7987):645–647. doi: 10.1016/s0140-6736(76)92460-0. [DOI] [PubMed] [Google Scholar]
  10. Dolen J. G., Carter W. A., Horoszewicz J. S., Vladutiu A. O., Leibowitz A. I., Nolan J. P. Fibroblast interferon treatment of a patient with chronic active hepatitis. Increased number of circulating T lymphocytes and elimination of rosette-inhibitory factor. Am J Med. 1979 Jul;67(1):127–131. doi: 10.1016/0002-9343(79)90088-3. [DOI] [PubMed] [Google Scholar]
  11. Einhorn S., Blomgren H., Strander H. Interferon and spontaneous cytotoxicity in man. I. Enhancement of the spontaneous cytotoxicity of peripheral lymphocytes by human leukocyte interferon. Int J Cancer. 1978 Oct 15;22(4):405–412. doi: 10.1002/ijc.2910220407. [DOI] [PubMed] [Google Scholar]
  12. Emödi G., O'Reilly R., Müller A., Everson L. K., Binswanger U., Just M. Effect of human exogenous leukocyte interferon in cytomegalovirus infections. J Infect Dis. 1976 Jun;133 (Suppl):A199–A204. doi: 10.1093/infdis/133.supplement_2.a199. [DOI] [PubMed] [Google Scholar]
  13. GRESSER I., DULL H. B. A VIRUS INHIBITOR IN PHARYNGEAL WASHINGS FROM PATIENTS WITH INFLUENZA. Proc Soc Exp Biol Med. 1964 Jan;115:192–196. doi: 10.3181/00379727-115-28867. [DOI] [PubMed] [Google Scholar]
  14. Greenberg H. B., Pollard R. B., Lutwick L. I., Gregory P. B., Robinson W. S., Merigan T. C. Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis. N Engl J Med. 1976 Sep 2;295(10):517–522. doi: 10.1056/NEJM197609022951001. [DOI] [PubMed] [Google Scholar]
  15. Greenberg S. B., Harmon M. W., Johnson P. E., Couch R. B. Antiviral activity of intranasally applied human leukocyte interferon. Antimicrob Agents Chemother. 1978 Oct;14(4):596–600. doi: 10.1128/aac.14.4.596. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Gresser I. Antitumor effects of interferon. Adv Cancer Res. 1972;16:97–140. doi: 10.1016/s0065-230x(08)60339-5. [DOI] [PubMed] [Google Scholar]
  17. Gresser I., Tovey M. G. Antitumor effects of interferon. Biochim Biophys Acta. 1978 Oct 27;516(2):231–247. doi: 10.1016/0304-419x(78)90009-4. [DOI] [PubMed] [Google Scholar]
  18. Hall C. B., Douglas R. G., Jr, Simons R. L., Geiman J. M. Interferon production in children with respiratory syncytial, influenza, and parainfluenza virus infections. J Pediatr. 1978 Jul;93(1):28–32. doi: 10.1016/s0022-3476(78)80594-0. [DOI] [PubMed] [Google Scholar]
  19. Havell E. A., Vilcek J. Production of high-titered interferon in cultures of human diploid cells. Antimicrob Agents Chemother. 1972 Dec;2(6):476–484. doi: 10.1128/aac.2.6.476. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Jao R. L., Wheelock E. F., Jackson G. G. Production of interferon in volunteers infected with Asian influenza. J Infect Dis. 1970 Apr;121(4):419–426. doi: 10.1093/infdis/121.4.419. [DOI] [PubMed] [Google Scholar]
  21. Johnson P. E., Greenberg S. B., Harmon M. W., Alford B. R., Couch R. B. Recovery of applied human leukocyte interferon from the nasal mucosa of chimpanzees and humans. J Clin Microbiol. 1976 Jul;4(1):106–107. doi: 10.1128/jcm.4.1.106-107.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Jones B. R., Coster D. J., Falcon M. G., Cantell K. Topical therapy of ulcerative herpetic keratitis with human interferon. Lancet. 1976 Jul 17;2(7977):128–128. doi: 10.1016/s0140-6736(76)92850-6. [DOI] [PubMed] [Google Scholar]
  23. Kaufman H. E., Meyer R. F., Laibson P. R., Waltman S. R., Nesburn A. B., Shuster J. J. Human leukocyte interferon for the prevention of recurrences of herpetic keratitis. J Infect Dis. 1976 Jun;133 (Suppl):A165–A168. doi: 10.1093/infdis/133.supplement_2.a165. [DOI] [PubMed] [Google Scholar]
  24. Kingham J. G., Ganguly N. K., Shaari Z. D., Mendelson R., McGuire M. J., Holgate S. J., Cartwright T., Scott G. M., Richards B. M., Wright R. Treatment of HBsAg-positive chronic active hepatitis with human fibroblast interferon. Gut. 1978 Feb;19(2):91–94. doi: 10.1136/gut.19.2.91. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Larsson A., Forsgren M., Hård af Segerstad S., Strander H., Cantell K. Administration of interferon to an infant with congenital rubella syndrome involving persistent viremia and cutaneous vasculitis. Acta Paediatr Scand. 1976 Jan;65(1):105–110. doi: 10.1111/j.1651-2227.1976.tb04415.x. [DOI] [PubMed] [Google Scholar]
  26. McIntosh K. Interferon in nasal secretions from infants with viral respiratory tract infections. J Pediatr. 1978 Jul;93(1):33–36. doi: 10.1016/s0022-3476(78)80595-2. [DOI] [PubMed] [Google Scholar]
  27. Merigan T. C., Rand K. H., Pollard R. B., Abdallah P. S., Jordan G. W., Fried R. P. Human leukocyte interferon for the treatment of herpes zoster in patients with cancer. N Engl J Med. 1978 May 4;298(18):981–987. doi: 10.1056/NEJM197805042981801. [DOI] [PubMed] [Google Scholar]
  28. Merigan T. C., Reed S. E., Hall T. S., Tyrrell D. A. Inhibition of respiratory virus infection by locally applied interferon. Lancet. 1973 Mar 17;1(7803):563–567. doi: 10.1016/s0140-6736(73)90714-9. [DOI] [PubMed] [Google Scholar]
  29. Merigan T. C., Sikora K., Breeden J. H., Levy R., Rosenberg S. A. Preliminary observations on the effect of human leukocyte interferon in non-Hodgkin's lymphoma. N Engl J Med. 1978 Dec 28;299(26):1449–1453. doi: 10.1056/NEJM197812282992608. [DOI] [PubMed] [Google Scholar]
  30. Neumann-Haefelin D., Sundmacher R., Skoda R., Cantell K. Comparative evaluation of human leukocyte and fibroblast interferon in the prevention of herpes simplex virus keratitis in a monkey model. Infect Immun. 1977 Aug;17(2):468–470. doi: 10.1128/iai.17.2.468-470.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. O'Reilly R. J., Everson L. K., Emödi G., Hansen J., Smithwick E. M., Grimes E., Pahwa S., Pahwa R., Schwartz S., Armstrong D. Effects of exogenous interferon in cytomegalovirus infections complicating bone marrow transplantation. Clin Immunol Immunopathol. 1976 Jul;6(1):51–61. doi: 10.1016/0090-1229(76)90060-x. [DOI] [PubMed] [Google Scholar]
  32. Pazin G. J., Armstrong J. A., Lam M. T., Tarr G. C., Jannetta P. J., Ho M. Prevention of reactivated herpes simplex infection by human leukocyte interferon after operation on the trigeminal root. N Engl J Med. 1979 Aug 2;301(5):225–230. doi: 10.1056/NEJM197908023010501. [DOI] [PubMed] [Google Scholar]
  33. Scott G. M., Cartwright T., LeDu G., Dicker D. Effect of human fibroblast interferon on vaccination in volunteers. J Biol Stand. 1978 Jan;6(1):73–76. doi: 10.1016/s0092-1157(78)80036-5. [DOI] [PubMed] [Google Scholar]
  34. Scott G. M., Csonka G. W. Effect of injections of small doses of human fibroblast interferon into genital warts. A pilot study. Br J Vener Dis. 1979 Dec;55(6):442–445. doi: 10.1136/sti.55.6.442. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Scullard G. H., Alberti A., Wansbrough-Jones M. H., Howard C. R., Eddleston A. L., Zuckerman A. J., Cantell K., Williams R. Effects of human leucocyte interferon on hepatitis B virus replication and immune responses in patients with chronic hepatitis B infection. J Clin Lab Immunol. 1979 Feb;1(4):277–282. [PubMed] [Google Scholar]
  36. Solov'ev V. D. The results of controlled observations on the prophylaxis of influenza with interferon. Bull World Health Organ. 1969;41(3):683–688. [PMC free article] [PubMed] [Google Scholar]
  37. Strander H. Anti-tumor effects of interferon and its possible use as an anti-neoplastic agent in man. Tex Rep Biol Med. 1977;35:429–435. [PubMed] [Google Scholar]
  38. Sundmacher R., Cantell K., Neumann-Haefelin D. Combination therapy of dendritic keratitis with trifluorothymidine and interferon. Lancet. 1978 Sep 23;2(8091):687–687. doi: 10.1016/s0140-6736(78)92809-x. [DOI] [PubMed] [Google Scholar]
  39. Sundmacher R., Cantell K., Skoda R., Hallermann C., Neumann-Haefelin D. Human leukocyte and fibroblast interferon in a combination therapy of dendritic keratitis. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 Nov 30;208(4):229–233. doi: 10.1007/BF00419377. [DOI] [PubMed] [Google Scholar]
  40. Sundmacher R., Neumann-Haefelin D., Cantell K. Successful treatment of dendritic keratitis with human leukocyte interferon. A controlled clinical study. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1976 Nov 18;201(1):39–45. doi: 10.1007/BF00410146. [DOI] [PubMed] [Google Scholar]
  41. Sundmacher R., Neumann-Haefelin D., Manthey K. F., Müller O. Interferon in treatment of dendritic keratitis in humans: a preliminary report. J Infect Dis. 1976 Jun;133 (Suppl):A160–A164. doi: 10.1093/infdis/133.supplement_2.a160. [DOI] [PubMed] [Google Scholar]
  42. Weimar W., Heijtink R. A., Schalm S. W., van Blankenstein M., Schellekens H., Masurel N., Edy V. G., Billiau A., De Somer P. Fibroblast interferon in HBsAg-positive chronic active hepatitis. Lancet. 1977 Dec 17;2(8051):1282–1282. doi: 10.1016/s0140-6736(77)92682-4. [DOI] [PubMed] [Google Scholar]
  43. Weimar W., Heijtink R. A., ten Kate F. J., Schalm S. W., Masurel N., Schellekens H., Cantell K. Double-blind study of leucocyte interferon administration in chronic HBsAg-positive hepatitis. Lancet. 1980 Feb 16;1(8164):336–338. doi: 10.1016/s0140-6736(80)90885-5. [DOI] [PubMed] [Google Scholar]
  44. Weimar W., Schellekens H., Lameijer L. D., Masurel N., Edy V. G., Billiau A., De Somer P. Double-blind study of interferon administration in renal transplant recipients. Eur J Clin Invest. 1978 Aug;8(4):255–258. doi: 10.1111/j.1365-2362.1978.tb00861.x. [DOI] [PubMed] [Google Scholar]
  45. Zarling J. M., Eskra L., Borden E. C., Horoszewicz J., Carter W. A. Activation of human natural killer cells cytotoxic for human leukemia cells by purified interferon. J Immunol. 1979 Jul;123(1):63–70. [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES