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tCho concentrations (mM) determined by in vivo 1H MRS of unprocessed tissues, by HRMAS 1H MRS of extracts, and by HR 1H MRS of tissue extracts of RIF-1 tumors 24 hours after treatment with saline or 200 mg/kg ZD6126. tCho determined in vivo and by HRMAS was significantly reduced (**P < .02).
