Table 5.
Comparison of the Levels of 80 Soluble Factors in Heat Inactivated Serum and Heat Inactivated Recalcified Plasma
| Factor | Heat Inactivated Serum | Heat Inactivated Recalcified Plasma | P* |
| ACRP-30 (microg/mL) | 15.9 ± 10.5 | 9.0 ± 5.8 | 0.000209 |
| Amphiregulin (pg/mL) | 7 ± 11 | 3 ± 5 | N.S. |
| ANG-2 (pg/mL) | 0 ± 0 | 0 ± 0 | N.S. |
| Apo A-1 (microg/mL) | 89.0 ± 16.6 | 70.0 ± 17.3 | 0.000433 |
| ApoB-100 (microg/mL) | 637 ± 147 | 544 ± 98 | 0.00831 |
| A-SAA (microg/mL) | 14.7 ± 4.80 | 11.4 ± 4.12 | 0.00228 |
| BDNF (ng/mL) | 7.23 ± 3.04 | 4.17 ± 1.54 | N.S. |
| CD14 (pg/mL) | 998 ± 2,439 | 9,922 ± 11,223 | N.S. |
| CD40L (pg/mL) | 48 ± 81 | 70 ± 63 | N.S. |
| CNTF (pg/mL) | 0 ± 0 | 0 ± 0 | N.S. |
| CRP (microg/mL) | 3.52 ± 0.84 | 2.33 ± 4.71 | N.S. |
| ENA-78 (pg/mL) | 637 ± 392 | 343 ± 122 | N.S. |
| Eotaxin (pg/mL) | 16 ± 26 | 25 ± 14 | N.S. |
| Eotaxin2 (ng/mL) | 1.66 ± 1.24 | 3.13 ± 2.33 | 0.000712 |
| E-Selectin (ng/mL) | 73.1 ± 16.7 | 70.0 ± 15.0 | N.S. |
| Exodus 2 (pg/mL) | 53 ± 21 | 106 ± 55 | 0.00976 |
| FGF Basic (pg/mL) | 218 ± 175 | 160 ± 219 | N.S. |
| Fibrinogen (ng/mL) | 174 ± 44.2 | 217 ± 76.7 | N.S. |
| G-CSF (pg/mL) | 29 ± 22 | 41 ± 19 | N.S. |
| GM-CSF (pg/mL) | 555 ± 267 | 623 ± 311 | N.S. |
| GRO-alpha (pg/mL) | 67 ± 61 | 36 ± 12 | N.S. |
| HGF (pg/mL) | 206 ± 124 | 224 ± 43 | N.S. |
| HGH (pg/mL) | 164 ± 148 | 159 ± 159 | N.S. |
| I-309 (pg/mL) | 27 ± 64 | 21 ± 38 | N.S. |
| ICAM-1 (ng/mL) | 145 ± 44.3 | 183 ± 48.7 | 0.00518 |
| IFN-α (pg/mL) | 1 ± 1.3 | 0.8 ± 1.3 | N.S. |
| IFN-γ (pg/mL) | 3 ± 9 | 3 ± 9 | N.S. |
| IL-11 (pg/mL) | 0 ± 0 | 0 ± 0 | N.S. |
| IL-12p40 (pg/mL) | 7 ± 15 | 6 ± 10 | N.S. |
| IL-16 (pg/mL) | 62 ± 19 | 66 ± 21 | N.S. |
| IL-1α (pg/mL) | 12 ± 26 | 11 ± 25 | N.S. |
| IL-1Ra (pg/mL) | 183 ± 328 | 150 ± 283 | N.S. |
| IL-2 (pg/mL) | 22 ± 32 | 21 ± 27 | N.S. |
| IL-2R (ng/mL) | 1.21 ± 0.67 | 1.49 ± 0.78 | N.S. |
| IL-2Rγ (pg/mL) | 0 ± 0 | 0 ± 0 | N.S. |
| IL-6 (pg/mL) | 7 ± 13 | 7 ± 12 | N.S. |
| IL-6R (pg/mL) | 30 ± 13 | 40 ± 10 | 0.00451 |
| IL-7 (pg/mL) | 5 ± 6 | 0.9 ± 2.6 | N.S. |
| IL-8 (pg/mL) | 7 ± 7 | 6 ± 9 | N.S. |
| IL-9 (pg/mL) | 771 ± 1,457 | 608 ± 1,259 | N.S. |
| IP-10 (pg/mL) | 128 ± 77 | 141 ± 55 | N.S. |
| ITAC (pg/mL) | 8 ± 10 | 8 ± 6 | N.S. |
| KGF (pg/mL) | 34 ± 17 | 26 ± 12 | N.S. |
| LEPTIN (ng/mL) | 2.15 ± 3.04 | 2.56 ± 3.06 | N.S. |
| L-Selectin (microg/mL) | 1.16 ± 0.32 | 1.06 ± 0.26 | N.S. |
| Lymphotactin (pg/mL) | 94 ± 107 | 86 ± 94 | N.S. |
| MCP-1 (pg/mL) | 456 ± 187 | 514 ± 153 | N.S. |
| MCP-2 (pg/mL) | 55 ± 15 | 47 ± 18 | N.S. |
| MCP-3 (pg/mL) | 0 ± 0 | 0 ± 0 | N.S. |
| MCP-4 (pg/mL) | 27 ± 19 | 30 ± 14 | N.S. |
| MDC (pg/mL) | 504 ± 127 | 463 ± 92 | N.S. |
| MIG (pg/mL) | 113 ± 61 | 119 ± 59 | N.S. |
| MIP-1α (pg/mL) | 60 ± 22 | 43 ± 32 | N.S. |
| MIP-1β (pg/mL) | 61 ± 35 | 69 ± 37 | N.S. |
| MIP-3α (pg/mL) | 6 ± 1 | 7 ± 2 | N.S. |
| MIP-3β (pg/mL) | 37 ± 13 | 56 ± 15 | 0.00714 |
| MMP-1 (ng/mL) | 3.17 ± 2.19 | 0.68 ± 0.46 | 0.00612 |
| MMP-10 (pg/mL) | 34 ± 45 | 0 ± 0 | N.S. |
| MMP-13 (pg/mL) | 60 ± 114 | 0 ± 0 | N.S. |
| MMP-2 (ng/mL) | 205 ± 35.7 | 125 ± 31.2 | 1.09 × 10-05 |
| MMP-3 (ng/mL) | 5.58 ± 2.99 | 1.44 ± 0.92 | 5.09 × 10-07 |
| MMP-9 (ng/mL) | 48.0 ± 35.6 | 15.4 ± 9.2 | 0.00217 |
| MPIF-1 (pg/mL) | 599 ± 184 | 616 ± 199 | N.S. |
| MPO (ng/mL) | 45.8 ± 13.6 | 32.0 ± 6.3 | 0.00206 |
| NAP-2 (microg/mL) | 2.80 ± 2.03 | 0.21 ± 0.20 | 8.47 × 10-05 |
| NT3 (pg/mL) | 10 ± 9 | 5 ± 8 | N.S. |
| OPG (pg/mL) | 3 ± 2 | 7 ± 4 | 0.00276 |
| OPN (ng/mL) | 2.13 ± 1.50 | 2.91 ± 2.68 | N.S. |
| PAI-1 Active (pg/mL) | 211 ± 179 | 97 ± 93 | N.S. |
| PAI-1 Total (ng/mL) | 4.33 ± 2.72 | 1.67 ± 1.54 | 0.00585 |
| PDGF-BB (pg/mL) | 165 ± 171 | 85 ± 198 | N.S. |
| RANTES (ng/mL) | 10.8 ± 12.2 | 3.9 ± 1.5 | N.S. |
| SDF-1β (pg/mL) | 173 ± 156 | 237 ± 172 | N.S. |
| TARC (pg/mL) | 74 ± 41 | 39 ± 10 | N.S. |
| TIMP-1 (ng/mL) | 121 ± 56.4 | 82.3 ± 17.1 | N.S. |
| TIMP-2 (ng/mL) | 109 ± 25.8 | 94.0 ± 16.2 | N.S. |
| TNF-α (pg/mL) | 46 ± 35 | 48 ± 38 | N.S. |
| TNF-RI (pg/mL) | 433 ± 115 | 413 ± 111 | N.S. |
| TNF-R2 (pg/mL) | 150 ± 46 | 584 ± 136 | 6.63 × 10-07 |
| VCAM-1 (ng/mL) | 46.5 ± 13.6 | 69.1 ± 12.0 | 0.000540 |
N.S. = Not Significant
*p values were calculated using Student's paired T tests and natural log transformed data.
Values are mean ± one standard deviation.