Table 2.
Main effects of calcium supplementation on bone mineral density at different sites
Site | No of studies | No of participants | Effect size*at end of trial | No of studies | No of participants | Effect size*after supplement ceased |
---|---|---|---|---|---|---|
Femoral neck (g/cm2) |
10 |
1073 |
0.07 (−0.05 to 0.19) |
5 |
617 |
0.10 (−0.06 to 0.26) |
Lumbar spine (g/cm2) |
11 |
1164 |
0.08 (−0.04 to 0.20) |
5 |
617 |
−0.01 (−0.16 to 0.17) |
Total body (g) |
9 |
953 |
0.14 (0.01 to 0.27)† |
1 |
96 |
0.00 (−0.40 to 0.40)‡ |
Upper limb (g/cm2) | 12 | 1579 | 0.14 (0.04 to 0.24)† | 6 | 840 | 0.14 (0.01 to 0.28)† |
Standardised mean difference (95% confidence interval); a standardised mean difference of 0.3 is regarded as small.22
P<0.05.
Single study only.