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. Author manuscript; available in PMC: 2006 Oct 13.
Published in final edited form as: Transfusion. 2005 Sep;45(9):1487–1495. doi: 10.1111/j.1537-2995.2005.00561.x

TABLE 2.

Clinical and laboratory findings in infants born to mothers immunized against HPA-9b (Maxa)

Case Child HPA-9b (Maxa) antibody present Maxa type of infant PLT nadir (×109/L) Time (days) to reach PLT count of 100 × 109/L Bleeding symptoms ICH Treatment Outcome
1 1 Yes Positive 5 18 Extensive petechiae at 12 hr Small ICH Random PLT transfusions, Days 1, 6, and 13 No neurologic sequelae
2 Yes Positive 6 10 Extensive petechiae and purpura at birth Major ICH Maternal and random PLT transfusion, Days 1 and 6 Permanent disability
2 1 Yes Positive 20 5 Moderate petechiae at birth No None Recovery
2 No Negative 225 None No None Normal infant
3 1 Yes Positive 7 18 Moderate petechiae at birth Small ICH PLT transfusion, Days 1 and 7 No neurologic
2 No Negative 235 None No None
4 1 Yes Positive 6 30 Moderate petechiae at birth No IV gamma globulin at 3 and 4 weeks of age Recovery
2 Yes Positive 237 None No Prenatal IV gamma globulin (last 2 months) Normal infant
5 1 Yes Positive 30 5 Moderate petechiae at birth No Random PLT transfusion, Day 2 Recovery
2 Yes Positive 231 None No Prenatal IV gamma globulin (last 2 months) Normal infant