A: Reduction of AIA in TFδCT/δCT mice. Arthritis was assessed at day 28 on a scale of 0 to 3 for five histopathological features (total score = 15) as described. Results are expressed as mean ± SEM of at least 13 mice in each group (*, P < 0.001 for TFδCT/δCT mice versus TF+/+ (WT) controls). B: Individual histological features of AIA in TFδCT/δCT mice. Arthritis was scored by histological analysis on a scale of 0 to 3 for synovitis, joint space exudate, soft tissue inflammation, cartilage damage, and bone damage. Results are expressed as means ± SEM [*, P < 0.05; **, P < 0.01; ***, P < 0.005 for TFδCT/δCT mice versus TF+/+ (WT) controls].