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. 2004 Jan;164(1):133–141. doi: 10.1016/S0002-9440(10)63104-5

Figure 6.

Figure 6

Effect of neutrophil depletion and anti-P-selectin therapy after ischemia. WT mice underwent 55 minutes of bilateral renal ischemia 4 hours after receiving an injection of ANS or control normal rabbit serum (150 μl/mouse), in combination with anti-P-selectin mAb or isotype-matched control mAb (40 μg/mouse), as shown. a: MPO activity was measured in the kidney tissue after 48 hours of reperfusion. b: BUN was measured at 24 and 48 hours after removal of clamps. Dashed line represents BUN measurement in normal animals. Numbers in parentheses represent numbers of animals studied at each point. P values are for comparison of treated groups with relevant control-treated groups.