Table 1.
Male
|
Female
|
|||
---|---|---|---|---|
Sham (n = 6) | RK (n = 8) | Sham (n = 6) | RK (n = 8) | |
BUN (mg/dl) | 14.2 ± 2.5 | 134.5 ± 29.0 | 12.2 ± 3.5 | 101.3 ± 32.1* |
Cr (mg/dl) | 0.9 ± 0.1 | 2.1 ± 0.8 | 0.8 ± 0.2 | 1.4 ± 0.6* |
Urine protein (mg/day) | 3.3 ± 2.7 | 159.0 ± 45.4 | 4.4 ± 1.3 | 96.4 ± 20.6* |
GS (% glomeruli) | 1.8 ± 1.5 | 19.6 ± 10.5 | 0.9 ± 0.6† | 7.8 ± 5.4* |
TI fibrosis score (0–5) | 0.09 ± 0.04 | 3.06 ± 1.42 | 0.04 ± 0.05 | 1.22 ± 1.03* |
Data is expressed as mean ± SD.
P <0.05 vs. male RK.
P <0.05 vs. male sham.
Abbreviations: GS, glomerulosclerosis; TI, tubulointerstitial.