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Bivariate plots of mean IOD values for thioredoxin (left) or APE/ref-1 (right) in relation to tumor hypoxia measurements (HP5, top) and interstitial fluid pressure (IFP, bottom). Tumor oxygenation was measured directly using an Eppendorf polarographic probe and the term HP5 signifies the proportion of measurements made within a tumor that were less than 5 mm/Hg. Interstitial fluid pressure was measured directly using a wick-in-needle technique, and the results are in mm/Hg.
