Dose-response effect of transplanted BMCs in myocardial repair. Groups of BALB/c mice were transplanted with the numbers of Ficoll-purified BMCs, obtained from normal donors, indicated on the x axis. The number of inflammatory cells per mm2 was determined by analysis of H&E 2 months after transplantation. Each symbol represents data obtained from an individual mouse. The horizontal lines represent the arithmetic mean of each group of mice. *, P < 0.001, in relation to control (saline-injected, no cells) group; Newman-Keuls multiple comparison test.