Figure 3.
A: Ischemia-induced changes in hindlimb blood flow monitored in vivo by laser Doppler perfusion imaging performed at day 10 after ischemia in nondiabetic mice treated with BM-MNCs isolated from nondiabetic or diabetic mice. In color coded images, normal blood flow is depicted in red. A marked reduction in blood flow of ischemic hindlimb is depicted in blue. B: Quantitative evaluation of blood flow expressed as a ratio of blood flow in ischemic foot to that in nonischemic one. Values are means ± SEM, n = 7 per group. *P < 0.05 versus PBS-injected nondiabetic animals. †P < 0.05 versus mice treated with nondiabetic BM-MNCs, #P < 0.05 versus PBS-injected diabetic animals. See legend to Figure 1.