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Effects of WIT003, a 20-HETE agonist analog, on proliferation of HUVECs. HUVECs were incubated with either 40 μmol/L palmitic acid or solvent alone (ethanol controls). There was no difference and therefore control data were combined. In the experimental group, cells were incubated with 1 μmol/L WIT003 for 48 hours and proliferation was assayed. WIT003 increased proliferation in HUVECs (n = 3, each by triplicate; *, P < 0.05 and #, P < 0.01, controls versus 1 and 10 μmol/L WIT003).
