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. 2005 Apr;166(4):1017–1028. doi: 10.1016/S0002-9440(10)62323-1

Figure 5.

Figure 5

Distribution and changes in apoptotic liver myofibroblasts in cirrhotic livers in rats untreated and treated with HGF. a: Distribution of apoptotic α-SMA-positive cells in liver sections obtained from cirrhotic livers on day 3 after HGF treatment. α-SMA-positive cells were detected by immunostaining (red) and apoptotic cells were detected using TUNEL staining (brown). b: Change in the number of apoptotic α-SMA-positive cells after HGF treatment. The number of cells double-positive for α-SMA and TUNEL staining was determined in liver sections. Rats were subjected to DMN administration for 5 weeks, followed by daily administration of HGF. Each value represents the mean ± SD (n = 8). *, P < 0.05. Original magnifications, ×200.