Skip to main content
. 2005 Jun;166(6):1637–1645. doi: 10.1016/s0002-9440(10)62474-1

Figure 1.

Figure 1

Acute hepatocytotoxicity in TRAF1−/− liver 20 hours after intratracheal treatment with rmTNF-α (5 μg/mouse). A: Intratracheal instillation of methylene blue and immediate necropsy confirmed treatment of pulmonary compartment. B and C: Gross liver pathology of TRAF1−/− mouse treated with diluent saline (B) or intratracheal rmTNF-α (C) (5 μg/mouse) as compared to BALB/c (WT) mouse treated with intratracheal rmTNF-α (D). E and F: Photomicrographs of H&E-stained TRAF1−/− liver 20 hours after intratracheal rmTNF-α treatment. G and H: Photomicrographs of H&E-stained WT (G) and TRAF1−/− (H) lung 20 hours after intratracheal rmTNF-α treatment. Original magnifications: ×200 (E, G, H); ×400 (F).