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HD exon 1 protein aggregates in SH-SY5Y and COS-7 cells. (a) SH-SY5Y cells expressing EGFP-HDQ74 (green). Note that the cell with multiple inclusions shows weak EGFP staining in the cytoplasm compared with the other transfected cells. Nuclei were stained with 4′,6-diamidino-2-phenylindole. (b) COS-7 cell transfected with HA-HDQ74 showing a single inclusion.
