Figure 7.

(A) p25 transgenic mice exhibit increased locomotor activity in an open field. p25 transgenic mice exhibited significantly more square crossings than wild-type littermates in an open field (*, P < .05; **, P < .01). Females (data not shown) showed the same effect beginning at 5 weeks of age. Numbers next to symbols represent the number of animals tested at each time point. (B) p25 transgenic mice spend increased time on the open arms of an elevated plus maze. p25 transgenic mice exhibited significantly greater time than wild-type littermates on the open arms of an elevated plus maze (*, P < .05; **, P < .01). Numbers within bars represent the number of animals in each group.