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. 2005 Aug;167(2):409–417. doi: 10.1016/s0002-9440(10)62985-9

Figure 6.

Figure 6

TGF-β1 depletion in pubertal glands results in increased frequency of cells in cycle but not in proliferating ER-α-positive mammary epithelial cells. A: Ki-67 and ER-α/Ki-67 co-localization frequency in endbud mammary epithelium of TGF-β1 heterozygote (+/−) and TGF-β1 wild-type (+/+) C57BL/6–129SV mice at 6 weeks of age. Three animals per genotype and at least 300 cells per animal were scored for presence of ER-α and Ki-67 immunoreactivity. B: Ki-67 and ER-α/Ki-67 co-localization frequency in the mammary epithelium of subtending ducts in the same tissues. Asterisks indicate significant difference from Tgfβ1 wild-type mean frequency (P < 0.01; t-test).