Skip to main content
. 2005 Aug;167(2):355–363. doi: 10.1016/S0002-9440(10)62981-1

Figure 6.

Figure 6

Relationship between p27 and mesangial cell size, general aspects. Cell size analyzed by flow cytometry revealed that mesangial cells isolated from p27 knockout mice were smaller than those isolated from wild-type mice (WT, **P < 0.01). Transfection of p27−/− mesangial cells with a p27 cDNA expression vector restored cells to a size comparable with that of wild-type (WT) mesangial cells (&&P < 0.01 versus p27−/−). Wild-type mesangial cells transfected with the p27 cDNA expression vector were also increased in size (##P < 0.01 versus WT or WT transfected with an empty vector). No change in cell size was found in mesangial cells transfected with an empty vector.