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ET causes adrenal gland lesions. Histopathological evaluation of adrenal glands at 12 hours in EF-treated (control) (a) and ET-treated (b) animals revealed necrosis and hemorrhage of the zona fasciculata (ZF) of the adrenal cortex induced by ET. The X-Zone (X) and zona glomerosa (ZG) were moderately necrotic whereas the medulla (M) was minimally affected by ET. Original magnifications, ×20.
