Figure 7.

Fibrin deposition and mucosal degeneration of GI tract caused by ET. Histopathology of GI tract mucosa after intravenous injection with 37.5 μg of EF, PBS, or 37.5 μg of ET. a: Areas of focal necrosis surrounded by normal tissue in the stomach mucosa of ET-treated mice (36 hours). b: Focal necrosis of the intestine 24 hours after ET treatment. c: Fibrin deposition in the villus tips in ET-treated animals (24 hours; right, arrows) as compared to normal villi from control animals (24 hours, left). M, mucosal surface; P, peritoneal cavity. Original magnifications: ×5 (a); ×10 (b); ×20 (c).