Table 1.
Age, Gender, Brain Weight, Total Phospholipids and Arachidonic Acid Content, Plasma Lipids, and Isoprostane iPF2α-VI Levels of the Different Groups of Animals Investigated
| 12/15LO−/− | ApoE−/− | 12/15LO−/−/ApoE−/− | |
|---|---|---|---|
| Age (months) | 12 | 12 | 12 |
| Gender (M/F) | 6/6 | 6/6 | 6/6 |
| Brain weight (g) | 0.47 ± 0.05 | 0.51 ± 0.06 | 0.50 ± 0.05 |
| Phospholipids (nmol/g) | 51.2 ± 5.1 | 50 ± 4.8 | 48.4 ± 5.2 |
| Arachidonic acid (μmol/g) | 9.4 ± 1.5 | 9.1 ± 1.4 | 8.9 ± 1.8 |
| Total cholesterol (mg/dl) | 125 ± 18 | 950 ± 45 | 1025 ± 50 |
| Triglycerides (mg/dl) | 80 ± 15 | 120 ± 22 | 115 ± 20 |
| HDL-cholesterol (mg/dl) | 105 ± 15 | 55 ± 8 | 58 ± 6 |
| iPF2α-VI (pg/ml) | 120 ± 12 | 458 ± 25 | 220 ± 18 |
Results are mean ± SEM.