Table 2.

Effect of Treatment with Various Dosages of RA at 9 Days 0 Hours on Kidney Development Assessed at E18

Dosage of RA (mg/kg body weight)	0	10	50	100	125
Number of litters examined	7	6	6	18	12
Number of fetuses that underwent resorption	1	6	8	17	11
(% total fetuses)	(1)	(7)	(11)	(9)	(10)
Number of live fetuses	82	85	66	172	102
% Live fetuses with any renal malformation	0	9	68	88	100
% Live fetuses with bilateral renal agenesis	0	0	20	66	100
% Live fetuses with unilateral renal agenesis*	0	0	21	16	0
% Live fetuses with nonagenesis renal malformations†	0	9	27	6	0

^*Contralateral kidney either normal or with nonagenesis renal malformations. 

^†Bilateral or unilateral with contralateral kidney being normal.