Table 2.
Dosage of RA (mg/kg body weight) | 0 | 10 | 50 | 100 | 125 |
Number of litters examined | 7 | 6 | 6 | 18 | 12 |
Number of fetuses that underwent resorption | 1 | 6 | 8 | 17 | 11 |
(% total fetuses) | (1) | (7) | (11) | (9) | (10) |
Number of live fetuses | 82 | 85 | 66 | 172 | 102 |
% Live fetuses with any renal malformation | 0 | 9 | 68 | 88 | 100 |
% Live fetuses with bilateral renal agenesis | 0 | 0 | 20 | 66 | 100 |
% Live fetuses with unilateral renal agenesis* | 0 | 0 | 21 | 16 | 0 |
% Live fetuses with nonagenesis renal malformations† | 0 | 9 | 27 | 6 | 0 |
Contralateral kidney either normal or with nonagenesis renal malformations.
Bilateral or unilateral with contralateral kidney being normal.