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Synaptic density in APP/CCL2 mouse brains. A: Mice at 14 months of age were tested for synaptic density by anti-synaptophysin staining. Images show 5-μm-thick coronal section of hippocampal region. B: Quantitative analysis of the density of synaptophysin staining in the hippocampus and the cortex. No statistical significance was observed among the group in either brain subregion. Original magnifications, ×40.
