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Schematic diagram of the “horizontal” (black arrows) and “vertical” (white arrows) comparisons performed in the microarray data analyses. dChip software14,15 was used to compare global expression datasets obtained with the HG-U133A array hybridized with the nonmetastatic (NM-2C5) and metastatic (CL16) primary tumors and the spontaneous metastatic deposits developing in the lung (Lung Mets) or in the thoracic lymph nodes (LN Mets) in SCID mice.
