Table 4.
Lists of Differentially Expressed Genes in the Horizontal and Vertical Comparisons: Metastatic Tumor versus Lung Metastases (P < 0.005, fc > 1.5)
| P value | fc | Gene description | Accession no. | Probe set |
|---|---|---|---|---|
| Genes up-regulated in the metastatic tumor (versus the lung metastases) | ||||
| 0.000728 | 1.72* | GalNAc-T1 | NM_020474.2 | 201724_s_at |
| 0.001816 | 1.61 | Oxysterol binding protein-like 10 | NM_017784.1 | 219073_s_at |
| 0.001868 | 1.87 | Solute carrier family 23 (nucleobase transporters), member 2 | AL389886 | 209236_at |
| 0.002554 | 2.09 | Transmembrane, prostate androgen-induced RNA | NM_020182.1 | 217875_s_at |
| 0.00297 | 1.66 | Plasminogen activator, tissue | NM_000930.1 | 201860_s_at |
| 0.00342 | 1.63 | Likely ortholog of rat GRP78-binding protein | NM_017870.1 | 218834_s_at |
| 0.003664 | 1.66 | SRY (sex determining region Y)-box 4 | NM_003107.1 | 201417_at |
| 0.004619 | 1.57 | Scavenger receptor class B, member 1 | NM_005505.1 | 201819_at |
| 0.004706 | 1.6 | Hypothetical protein LOC283687 | AF249277.1 | 210242_x_at |
| Genes up-regulated in the lung metastases (versus the metastatic tumor) | ||||
| 0.00052 | 6.83 | Surfactant, pulmonary-associated protein C | J03553 | 38691_s_at |
| 0.000576 | 2† | Neuroblastoma, suppression of tumorigenicity 1 | NM_005380.1 | 201621_at |
| 0.001028 | 1.75 | Tight junction protein 1 (zona occludens 1) | NM_003257.1 | 202011_at |
| 0.001141 | 2.77 | Human HL14 gene encoding β-galactoside-binding lectin, 3 end, clone 2 | M14087.1 | 216405_at |
| 0.001547 | 1.53 | Phosphoenolpyruvate carboxykinase 2 (mitochondrial) | NM_004563.1 | 202847_at |
| 0.001648 | 1.8† | Neuroblastoma, suppression of tumorigenicity 1 | D28124 | 37005_at |
| 0.001781 | 751.48 | Surfactant, pulmonary-associated protein C | BC005913.1 | 211735_x_at |
| 0.002132 | 1.68 | VAMP (vesicle-associated membrane protein)-associated protein A, 33 kd | AF154847.1 | 208780_x_at |
| 0.002596 | 2.57 | New member of the thymosininterferon-inducible multigene family | AL133228 | 216438_s_at |
| 0.003235 | 1.93 | Pilin-like transcription factor | NM_012228.1 | 218773_s_at |
| 0.003408 | 1.53 | Ets variant gene 5 (ets-related molecule) | X76184.1 | 216375_s_at |
| 0.003577 | 2.02 | Ubiquitin specific protease 1 | AW499935 | 202412_s_at |
| 0.003774 | 1.68 | Apolipoprotein C-I | NM_001645.2 | 204416_x_at |
| 0.003932 | 1.82 | Serine/arginine repetitive matrix 2 | AI655799 | 208610_s_at |
| 0.004159 | 1.94 | Serotonin-7 receptor pseudogene | U86813.1 | 216098_s_at |
| 0.004508 | 1.68 | Endothelin receptor type B | M74921.1 | 204271_s_at |
| 0.004889 | 2.37 | Transmembrane 4 superfamily member 2 | NM_004615.1 | 202242_at |
*
Refuted by Q-PCR.
†
Validated by Q-PCR.