Table 6.
Lists of Differentially Expressed Genes in the Horizontal and Vertical Comparisons: Lung Metastases versus LN metastases (P < 0.005, fc > 1.5)
| P value | fc | Gene description | Accession no. | Probe set |
|---|---|---|---|---|
| Genes up-regulated in the lung metastases (versus the LN metastases) | ||||
| 0.000266 | 6.63 | Surfactant, pulmonary-associated protein C | J03553 | 38691_s_at |
| 0.000335 | 1.5† | S100 calcium binding protein A9 (calgranulin B) | NM_002965.2 | 203535_at |
| 0.000925 | 1.62† | Homeo box B13 | U57052.1 | 209844_at |
| 0.00099 | 1.99† | Matrix metalloproteinase 14 (membrane-inserted) | NM_004995.2 | 202828_s_at |
| 0.001212 | 2.42 | Sine oculis homeobox homolog 3 (Drosophila) | NM_005413.1 | 206634_at |
| 0.001642 | 1.63 | Discs, large (Drosophila) homolog-associated protein 1 | NM_004746.1 | 206490_at |
| 0.001999 | 1.56 | Interleukin 1 receptor antagonist | BE563442 | 216245_at |
| 0.002368 | 1.62 | Transition protein 2 (during histone to protamine replacement) | NM_005425.1 | 207736_s_at |
| 0.00255 | 1.55 | Suppression of tumorigenicity 7 like | NM_017744.1 | 219964_at |
| 0.003281 | 1.64 | Homo sapiens cDNA: FLJ21911 fls, clone HEP03855 | AK025564.1 | 216780_at |
| 0.003664 | 1.54 | H. sapiens cDNA: FLJ21198 fls, clone COL00220. | AK024851.1 | 216740_at |
| 0.004192 | 1.67 | KIAA0570 gene product | AK023845.1 | 215013_s_at |
| 0.004537 | 1.85 | SPARC-like 1 (mast9, hevin) | NM_004884.1 | 200795_at |
| 0.004661 | 2.05 | Transmembrane 4 superfamily member 1 | M90657.1 | 209387_s_at |
| Genes up-regulated in the LN metastases (versus the lung metastases) | ||||
| 0.00249 | 1.51 | Syndecan 2 | J04621.1 | 212154_at |
†
Validated by Q-PCR.