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. 2005 May;166(5):1565–1579. doi: 10.1016/S0002-9440(10)62372-3

Table 7.

Distribution of the Differentially Expressed Genes in Metastasis-Related Groups Generated from the Horizontal and Vertical Comparisons in Vivo and from the Cell Line Comparisons in Vitro

In vivo Genes up-regulated
Nonmetastatic tumor
Metastatic tumor
Lung metastases
LN metastases
Compared samples fc P < 0.001 P < 0.005 P < 0.05 P < 0.001 P < 0.005 P < 0.05 P < 0.001 P < 0.005 P < 0.05 P < 0.001 P < 0.005 P < 0.05
NM-2C5T M-4A4T fc > 1.5 142 386 1068 219 416 697
fc > 3 17 43 92 55 77 101
NM-2C5T M-4Lu fc > 1.5 117 323 969 193 403 660
fc > 3 12 31 82 51 74 90
NM-2C5T M-4LN fc > 1.5 114 329 886 190 379 680
fc > 3 15 35 87 48 67 95
M-4A4T M-4Lu fc > 1.5 1 9 69 2 17 88
fc > 3 0 0 6 1 2 8
M-4A4T M-4LN fc > 1.5 14 56 279 14 58 184
fc > 3 2 8 27 3 9 17
M-4Lu M-4LN fc > 1.5 4 14 50 0 1 20
fc > 3 1 1 4 0 0 0
In vitro Nonmetastatic line Metastatic line Highly metastatic line
NM-2C5 M-4A4-GFP fc > 1.5 363 361
fc > 3 40 28
NM-2C5 LM3 clone 16 fc > 1.5 1708 930
fc > 3 198 113
M-4A4-GFP LM3 clone 16 fc > 1.5 1473 336
fc > 3 155 70