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. 2006 Apr;168(4):1335–1344. doi: 10.2353/ajpath.2006.051181

Figure 4.

Figure 4

Elimination of autologous HIV-1-infected MDMs from brains of ethanol versus control hu-PBL-NOD/SCID HIVE mice. CD68+ MDMs (A), CD8+ lymphocytes (B), and HIV-1 p24+ MDMs (C) were counted in brain tissue sections of control and ethanol (EtOH)-fed hu-PBL-NOD-SCID HIVE mice at weeks 1 and 2 after intracerebral inoculation of HIV-1-infected MDMs. EtOH-fed mice demonstrated inefficient elimination of MDM/HIV-1 p24+ MDMs (C) compared with pair-fed controls. Value represents mean ± SEM per 5-μm section; six to nine sections were analyzed for each animal. *P < 0.03; **P < 0.04; #P < 0.02 (EtOH versus control).