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. 2006 Apr;168(4):1210–1226. doi: 10.2353/ajpath.2006.050482

Figure 7.

Figure 7

Blocking of FcRn-mediated transcytosis of IgG-virions complexes in villus explants from immune donors. a: Transcytosis of Toledo-EGFP virions (green) and uptake by villus core macrophages stained with CD68 (red) in control untreated explants. Explants briefly treated with trypsin (b), and explants infected in the presence of soluble protein A (c) did not transcytose IgG-virions across syncytiotrophoblasts to villus core macrophages. STB, syncytiotrophoblast; CTB, cytotrophoblasts; VC, villus core; Mφ, macrophages.