Table 2.
Tumor Growth and Morphology in SCID Mouse
| SCID mice (n) | Cell line | Mean tumor size (mm) | Morphology | Vascularization
|
|
|---|---|---|---|---|---|
| CP | SN | ||||
| Experiment 1 | |||||
| 3 | HT1080 | 21 × 16 | Low differentiated sarcoma with extensive necrosis | − | + |
| 5 | HT1080 FUSaEGFP | 12 × 10 | Low differentiated sarcoma with extensive necrosis | − | + |
| Clone 1 | |||||
| 5 | HT1080 | 10 × 11 | Liposarcoma with abnormal lipoblasts and capillary network | + | − |
| FUS-DDIT3EGFP | |||||
| Clone 1 | |||||
| 5 | HT 1080 | 11 × 14 | Liposarcoma with abnormal lipoblasts and capillary network | + | − |
| DDIT3-EGFP | |||||
| Clone 1 | |||||
| Experiment 2 | |||||
| 2 | HT1080 | 18 × 12 | Low differentiated sarcoma | − | + |
| 5 | HT1080 | 10 × 6 | Liposarcoma with abnormal lipoblasts and capillary network | + | − |
| FUS-DDIT3-EGFP | |||||
| Clone 1 | |||||
| 5 | HT1080 | 11 × 9 | Liposarcoma with abnormal lipoblasts and capillary network | + | − |
| DDIT3-EGFP | |||||
| Clone 1 | |||||
CP, capillary type; SN, sinusoid type.