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. 2006 Jun;168(6):1869–1878. doi: 10.2353/ajpath.2006.050623

Figure 3.

Figure 3

Morphology of adult ventral prostate lobes following neonatal DES. Histological examination identified apparent increases in lumen size and epithelial infolding in ArKO control tissue (b) compared to WT (a). Following neonatal DES treatment VP from WT mice aged 90 (b) showed apparent ductal regression as indicated by narrowing of ducts and reduction in lumen size and an apparent increase in epithelial infolding, which became more pronounced at 180 days (c). DES-treated ArKO VPS at 90 (e) and 180 days (f) showed similar histological responses to those seen in WT tissue, although lumen appeared to be larger than those seen in WT tissues. Staining, H & E; magnification objective, ×4; scale bar = 200 μm.