Figure 5.

Induction of local inflammatory response in adult prostate following neonatal DES. DES treatment of animals was also associated with the manifestation of a local inflammatory response in all prostate lobes of both ArKO and WT. Inflammation was characterized by a significant concentration of leukocytes within the stroma and epithelium of tissues (b, f, and h, arrowheads). Inflammatory cells were also identified invading the epithelium (a and b, insets). Staining, H & E; magnification objective, ×40; scale bar = 100 μm; magnification, ×100 (inset), scale bar = 20 μm (inset).