Table 1. Effect of LOVA and SIMVA on total cellular cholesterol concentration.
Total cholesterol concentration, measured as free and esterified cholesterol, was calculated as the average of three experiments each performed in triplicates expressed as μg of cholesterol/mg of protein. ns, not significant; *P<0.05 and **P<0.01.
Cholesterol concentration | |
---|---|
Untreated | 785.7±56.2 |
Lovastatin | |
1 μM | 694.9±40.0ns |
10 μM | 602.2±23.5* |
50 μM | 682.4±31.8* |
Simvastatin | |
1 μM | 615.4±75.9ns |
10 μM | 590.2±32.7** |
50 μM | 569.6±24.7** |