Table 1. Binding characteristics of CB3GA and its fragments to recombinant NA.

The structures of analogues are depicted in Figure 2. Inhibition constants (K_i) were determined by kinetic inhibition studies.

Compound	Ki (μM)
1	56.5±4
2	12.5±2
3	12.8±1.9
4	2.9±0.2*
5	0.28±0.04
6	0.13±0.05
7	17.1±1.9
8	4.3±0.7
9	No detectable binding

*The value of 2.1±0.2 μM for compound 4 was determined by difference spectra titrations.